Hereditary Spastic Paraplegia (HSP) - Dr. Ayman Nashashibi
Hereditary Spastic Paraplegia (HSP) - Dr. Ayman Nashashibi Dr. Ayman Nashashibi - Familial Spastic Paraparesis or Hereditary Spastic Paraplegia (HSP), is identified is a group of hereditary, degenerative, neurological disorders that primarily affect the upper motor neurons, where the upper motor neurons and the spinal cord transmit signals to the lower motor neurons as a mean to carry commands to the muscles. In the case of HSP, upper motor neurons gradually degenerate, causing the muscles to stop receive the correct commands, causing increased muscle stiffness known as “spasticity” illustration courtesy of Semantic Scholar Prevalence Hereditary spastic paraplegia has been reported in nearly every country with an estimated frequency ranging from 0.5 to 12 people per 100,000, but there isn’t an accurate data. However, based on the most recent study by the Norwegian study rate of 7.4/100,000 of population has been estimated, without any rep...